In recent years, with the continuous development of medical technology, the early diagnosis and treatment of ischemic stroke has been effectively promoted. Among them, mechanical thrombectomy is widely used due to its advantages such as long treatment time window and high vascular patency rate. This has also reduced the risk of death to a certain extent and improved the prognosis of patients. However, studies have found that some ischemic stroke patients may still experience recurrent vertigo after mechanical thrombectomy, which not only increases their physical discomfort, but also increases the patient's mental stress, affects the rehabilitation process, and increases the risk of poor prognosis. There may be many reasons for dizziness in ischemic stroke patients after mechanical thrombectomy.
1. Lesion site
Studies have shown that posterior circulation lesions are a risk factor for vertigo in patients with ischemic stroke. Compared with other lesion sites, cerebral ischemia caused by posterior circulation infarction will aggravate the apoptosis of vestibular nucleus cells, leading to vestibular system dysfunction. Moreover, after mechanical thrombectomy, although the blood supply of the posterior circulation is restored, the large-scale apoptosis of vestibular nucleus cells requires a long time to repair, which will cause the patient's bilateral vestibular system resting potential to be unbalanced in the short term after surgery, leading to the occurrence of vertigo.
2. Combined with hypertension
If the blood pressure of stroke patients fluctuates greatly after mechanical thrombectomy, it will affect local blood circulation, increase ischemic and hypoxic damage to brain tissue, and affect the recovery of neurological function, causing vestibular nerve function disorder in patients and triggering vertigo symptoms. Patients with combined hypertension have greater blood pressure fluctuations, which will increase the degree of cerebral vasospasm or dilation to a certain extent, leading to local brain tissue hypoperfusion, triggering cell apoptosis, causing vestibular nerve nucleus damage, reducing vestibular information processing ability, and ultimately increasing the risk of vertigo.
3. CRP
Inflammatory response runs through the entire process of vascular intimal damage and atherosclerotic plaque development, and plays an important role in the occurrence and development of stroke. Ischemic stroke patients often have a micro-inflammatory state in their bodies, which will lead to abnormally elevated CRP levels. During surgery, the patient's atherosclerotic plaque will release a large number of inflammatory factors, which will further release a large amount of CRP, causing persistent damage to vestibular nerve cells and increasing the risk of dizziness.
Patients with ischemic stroke have a certain risk of vertigo after mechanical thrombectomy. The lesion site, combined hypertension and CRP are all influencing factors for the occurrence of vertigo.